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Subproject
R1 - Magnesium Degradation
Development of biocompatible magnesium alloys and investigations
into their degradation behaviour
This subproject involves the development of magnesium-based alloys for degradable implants. These implant materials are to be suitable for use with both hard tissue (i.e. of high stability) and soft tissue (i.e. of high ductility). . ... >> |
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Subproject
R2 - Magnesium Sponges
Magnesium sponges as bioresorbable implants
On the basis of previous results, degradable osseous implants will be refined for use in weight-bearing areas. Novel hybrid ceramic magnesium sponge structures will be designed to ensure enhanced resilience and biocompatibility, as well as a suitable, specially tailored rate of degradation.
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Subproject
R4 - Mechanical Processing
Functionally tailored processing of medical implants
The aim of subproject R4 is to develop and produce degradable small-fragment implants made of magnesium-based alloys while controlling implant degradation by tailoring, in a defined manner, the surface and peripheral-zone properties that arise from mechanical processing. ... >> |
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Subproject
R6 - Degradable Bone Implants
“Degradable” osteosynthesis – optimising bone regeneration through stability-driven implant absorption using absorbable light metals
The aim of this subproject is to develop optimal resorbable implants, made of magnesium alloys, for osteosynthesis applications in weight-bearing bone. These resorbable light metals are of significantly higher strength than the polymers previously used as resorbable implant material.
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Subproject R7 -
Magnesium Meshes
Use of stabilising magnesium meshes to facilitate cardiovascular tissue replacement in high-pressure systems
In cardiovascular surgery, reconstructive surgical techniques are the therapy of choice for cardiac valves and vascular replacement, and for restoring damaged heart muscle. ... >> |
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Subproject
D1 - New Medical Ceramics
Biomimetic synthesis of ceramics for a biocompatible ossicular chain replacement prosthesis
The aim of this project is to develop a middle ear prosthesis for reconstituting the transmission function of the ossicular chain. Findings from the first funding period have provided valuable approaches to solving this problem and have shown that a uniformly structured material is unable to do justice to the complex, local and functionally different requirements involved. ... >> |
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Subproject
D2 - Nerve-Electrode Interface
Development of a new electrode array for an optimised interface between neural tissue and electrodes
The aim of the project is to fundamentally improve the functional restoration of hearing ability in the deaf by electrostimulation of the auditory nerve (cochlear implants) or the central auditory system (brainstem implants, midbrain implants). ... >> |
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Subproject
D4 - Ceramic Implants
Automated processing of free-form surfaces and testing of low-wear ceramic implants
With their outstanding resistance to wear, ceramics are ideally suited for use as implant material in endoprosthetics. Rates of loosening due to wear can be markedly reduced compared to those observed with conventional prostheses. ... >> |
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Subproject
D6 - Design of Total Endoprostheses
Numeric simulation with a view to stress-compatible design
of total endoprostheses and implants
Aseptic loosening of the prosthesis remains a prevailing problem in artificial joint replacement. Loosening may be caused, for example, by stress shielding in the bone tissue surrounding the prosthesis. ... >> |
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Subproject
D7 - Implant Surfaces
Functionalising implant surfaces
The chief aim is the improved, permanent anchoring of endoprostheses. This will be achieved by the development of ultra-thin, functional polymer coatings that act as a contact interface between bone and implant. ... >> |
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Subproject D8 - Dental Implant Abutments
Material optimisation and functionalisation of dental implant abutments
The aims, with a view towards improving the service life of dental implants, are twofold. Firstly, the corrosion resistance and mechanical stability of ceramic abutments is to be to optimised and, by means of biomechanic stress tests and finite-element (FE) analyses, verified. ... >> |
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Subproject D9 - Biomimetic Ceramics
Production, processing and mechanical testing of biomimetic ceramics
While ceramic materials for implants show low levels of wear, they exhibit insufficient elastic deformability. Peak stresses may therefore cause rupture. In many areas subject to particularly high mechanical stress, nature makes use of hard but elastic composite materials. ... >> |
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Subproject D10 - Implants of Variable Rigidity
Influencing bone healing using implants of variable rigidity based on shape memory alloys
Bone healing can be influenced by mechanical stimuli, making it dependent on the rigidity of stabilising internal osteosynthesis. In this subproject, implants are created on the basis of commercially available shape memory alloys whose rigidity can be actively changed by means of short-term percutaneous induction heating. ... >> |
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Subproject T1 - Mikrostrukturierte Cochlea-Implantat-Elektroden
Cochlear implantation, in which an electrode array is inserted into the inner ear, is the standard present-day procedure in the treatment of deaf patients. ... >> |
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